Guyton and Hall Textbook of Medical Physiology, 12e

Guyton and Hall Textbook of Medical Physiology, 12e

John E. Hall

Language: English

Pages: 1120

ISBN: 1416045740

Format: PDF / Kindle (mobi) / ePub

The twelfth edition of Guyton and Hall Textbook of Medical Physiology continues this best-selling title's long tradition as one of the world's favorite physiology textbooks. The immense success of this book is due to its description of complex physiologic principles in language that is easy to read and understand. Now with an improved color art program, thorough updates reflecting today's medicine and science, and accessible online at Student Consult, this textbook is an excellent source for mastering essential human physiology knowledge.

  • Learn and remember vital concepts easily thanks to short, easy-to-read, masterfully edited chapters and a user-friendly full-color design.
  • See core concepts applied to real-life situations with clinical vignettes throughout the text.
  • Discover the newest in physiology with updates that reflect the latest advances in molecular biology, cardiovascular, neurophysiology, and gastrointestinal topics.
  • Visualize physiologic principles clearly with over 1000 bold, full-color drawings and diagrams.
  • Distinguish core concepts from more in-depth material with a layout that uses gray shading to clearly differentiate between "need-to-know" and "nice-to-know" information.
  • Access the complete contents online at Student Consult along with bonus resources such as image banks, self-assessment questions, physiology animations, and more!

This new edition continues the long tradition of "Guyton" as one of the world's favorite physiology textbooks.














the apex and outer surfaces of the ventricles ahead of the intraventricular surfaces. That is, the T wave becomes ­abnormal when the normal sequence of repolarization does not occur. Several factors can change this sequence of repolarization. 141 U n i t III from the chest wall. In other words, the current of injury is coming from the back of the heart opposite to the anterior chest wall, which is the reason this type of electrocardio­ gram is the basis for diagnosing posterior wall infarction.

instance, that the permeability for glucose molecules is 0.6 times that for water molecules, whereas the permeability for albumin molecules is very, very slight, only 1/1000 that for water molecules. A word of caution must be issued at this point. The capillaries in various tissues have extreme differences in their permeabilities. For instance, the membranes of the liver capillary sinusoids are so permeable that even plasma proteins pass freely through these walls, almost as easily as water and

membrane patch being studied. By varying the concentrations of different ions, as well as the voltage across the membrane, one can determine the transport characteristics of the single channel and also its gating properties. Chapter 4  Transport of Substances Through Cell Membranes Open sodium channel Simple diffusion Vmax Rate of diffusion 0 3 U n i t II Picoamperes 3 Facilitated diffusion 0 0 2 A 4 6 Milliseconds 8 10 Concentration of substance Figure 4-7  Effect of

inhibition, Pflugers Arch 457:609, 2009. Tian J, Xie ZJ: The Na-K-ATPase and calcium-signaling microdomains, Physiology (Bethesda) 23:205, 2008. chapter 5 Electrical potentials exist across the membranes of virtually all cells of the body. In addition, some cells, such as nerve and muscle cells, are capable of generating rapidly changing electrochemical impulses at their membranes, and these impulses are used to transmit signals along the nerve or muscle membranes. In other types of cells,

system, smooth muscle can be stimulated to contract by multiple types of signals: by nervous signals, by hormonal stimulation, by stretch of the muscle, and in several other ways. The principal reason for the difference is that the smooth muscle membrane contains many types of receptor proteins that can initiate the contractile process. Still other receptor proteins inhibit smooth muscle contraction, which is another difference from skeletal muscle. Therefore, in this section, we discuss nervous

Download sample